Survival and New Prognosticators in Metastatic Seminoma: Results From the IGCCCG-Update Consortium.
Joerg BeyerLaurence ColletteNicolas SauvéGedske DaugaardDarren R FeldmanTorgrim TandstadAlexey A TryakinOlof StahlEnrique Gonzalez-BillalabeitiaUgo De GiorgiStephane CulineRonald de WitAaron Richard HansenMarko BebekAngelika TerbuchCostantine AlbanyMarcus HentrichJourik A GietemaHelene F S NegaardRobert A HuddartAnja LorchFay H CaffertyDaniel Y C HengChristopher J SweeneyEric WinquistMichal ChovanecChristian Daniel FankhauserDaniel StarkPeter S GrimisonAndrea NecchiBen TranAxel HeidenreichJonathan ShamashCora N SternbergDavid J VaughnIgnacio DuranCarsten BokemeyerAnna PatrikidouRichard CathomasSamson AsseleSilke Gillessen Sommernull nullPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)
PFS and OS in metastatic seminoma significantly improved in our modern series compared with the original data. The original IGCCCG classification retains its relevance, but can be further refined by adding LDH at a cutoff of 2.5× upper limit of normal as an additional adverse prognostic factor.