Severity of acute phase reaction in children receiving the first dose of zoledronic acid and the impact of the underlying condition: a cross-sectional study.
Sapna NayakLauren RaynerM Zulf MughalGeorgia McKinneyAvril MasonSze Choong WongRaja PadidelaAmish ChinoyPublished in: Archives of disease in childhood (2024)
Most patients had a mild APR not requiring overnight hospital admission, after their first ZA dose. However, certain groups seem to suffer more severe APR and may warrant consideration of inpatient monitoring with the first infusion.