Fetal overnutrition and offspring insulin resistance and β-cell function: the Exploring Perinatal Outcomes among Children (EPOCH) study.

Katherine Ann SauderC W HockettB M RinghamD H GlueckD Dabelea

Published in: Diabetic medicine : a journal of the British Diabetic Association (2017)

Intrauterine exposure to diabetes or obesity is associated with greater offspring insulin resistance than non-exposure, supporting the hypothesis that fetal overnutrition results in metabolic abnormalities during childhood and adolescence.

Keyphrases

insulin resistance
high fat diet
type diabetes
adipose tissue
metabolic syndrome
high fat diet induced
skeletal muscle
polycystic ovary syndrome
glycemic control
young adults
depressive symptoms
cardiovascular disease
weight loss
body mass index
weight gain
physical activity