Direct Factor X sequestration by systemic amyloid light-chain amyloidosis.
Haruko TashiroRyosuke ShirasakiMasato WatanabeKazuo KawasugiYoshihisa TakahashiNaoki ShirafujiPublished in: Clinical case reports (2018)
We present a lymphoplasmacytic lymphoma patient with Factor X (FX) deficiency. Despite the absence of FX inhibitor, the administration of fresh frozen plasma and anti-inhibitor coagulant complex did not increase the FX level. The autopsy showed that massive amyloid depositions to multiple organs and FX existed in union with amyloidosis.