Assessment of Pharmacokinetic Parameters of Daidzein-Containing Nanosuspension and Nanoemulsion Formulations After Oral Administration to Rats.
Esra DemİrtÜrkAfife Busra Ugur KaplanMeltem CetinKübra AkıllıoğluMeltem Dönmez KutluSeda KöseFazilet AksuPublished in: European journal of drug metabolism and pharmacokinetics (2022)
It revealed that nanoscale size is an important factor to overcome any dissolution rate barriers to oral bioavailability of the low water-soluble compound. Nanoemulsion and nanosuspension formulations are beneficial dosage forms to increase the oral bioavailability of Biopharmaceutical Classification System (BCS) Class II and Class IV compounds.