Sertraline Alleviates Chronic Prostatitis by Regulating the TRPV1 Channel.

Yongfeng LaoYanan BaiXin GuanJian WangYanan WangRongxin LiYongqiang DingZhilong Dong

Published in: Journal of inflammation research (2024)

The results revealed the anti-inflammatory effect of sertraline for RWPE-1 cells and EAP mice, and the potential mechanism was regulating the TRPV1 channel. It indicated that sertraline might serve as a complementary anti-inflammatory agent for CP.

Keyphrases

anti inflammatory
induced apoptosis
neuropathic pain
cell cycle arrest
single cell
endoplasmic reticulum stress
type diabetes
signaling pathway
mouse model
spinal cord injury
spinal cord
metabolic syndrome
skeletal muscle
human health
cell proliferation
climate change
wild type