Effects of Kappa opioid receptor blockade by LY2444296 HCl, a selective short-acting antagonist, during chronic extended access cocaine self-administration and re-exposure in rat.
Marta ValenzaKyle A WindischEduardo R ButelmanBrian ReedMary Jeanne KreekPublished in: Psychopharmacology (2020)
Overall, the KOPr antagonist attenuated escalated cocaine consumption in a rat model of extended access cocaine self-administration.