High mean arterial pressure target to improve sepsis-associated acute kidney injury in patients with prior hypertension: a feasibility study.
Antoine DewitteAurore LabatPierre-Antoine DuvignaudGauthier BoucheOlivier Joannes-BoyauJean RipocheGilles HilbertDidier GrusonSébastien RubinAlexandre OuattaraAlexandre BoyerChristian CombePublished in: Annals of intensive care (2021)
In the early stage of sepsis-associated AKI, a high-MAP target in patients with a history of hypertension was associated with a higher CrCl, but did not affect the kidneys' ability to concentrate urine, which may reflect no effect on tubular function.