Hypnotic Use and the Risk of Cardiovascular Diseases in Insomnia Patients.

Yao XieShiyu ZhuShuang WuChang LiuJian ShenChunna JinHong MaMeixiang Xiang

Published in: European journal of preventive cardiology (2024)

Our findings suggested the heterogeneous associations between different categories of hypnotics and incident cardiovascular events in individuals with insomnia. Both observational and genetic evidence raised safety concerns regarding the cardiovascular impact of benzodiazepines. No cardiovascular hazard of Z-meds was discovered in the UKB population with insomnia.

Keyphrases

cardiovascular events
cardiovascular disease
end stage renal disease
sleep quality
coronary artery disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
type diabetes
genome wide
gene expression
copy number
patient reported outcomes