Cellular and extracellular white matter alterations indicate conversion to psychosis among individuals at clinical high-risk for psychosis.
Felix L NägeleFelix Leonard NägeleLisa V BitzanMarius MußmannJonas RauhMarek KubickiGregor LeichtMartha E ShentonAmanda E LyallChristoph MulertPublished in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2020)
Our study suggests that cellular (FAT) and extracellular (FW) white matter alterations are associated with positive symptom severity and indicate an elevated illness risk among CHR individuals.