MHC Class I Masking to Prevent AMR in a Porcine Kidney Transplantation Model in Alloimmunized Recipients.

Delphine KervellaJulien BranchereauThomas PrudhommeVéronique Nerrière-DaguinKarine RenaudinDavid MinaultJérémy HervouetBernard MartinetSarah BruneauStéphanie Le Bas-BernardetGilles Blancho

Published in: Transplantation direct (2023)

Despite a partial protective effect of swine leukocyte antigen I masking with JM1E3 in vitro, ex vivo perfusion of the kidney with JM1E3 before transplantation was not sufficient alone at preventing or delaying AMR in highly sensitized recipients.

Keyphrases

kidney transplantation
contrast enhanced
cell therapy
stem cells
antimicrobial resistance
peripheral blood
computed tomography