Predicting HBsAg clearance in genotype A chronic hepatitis B using HBsAg epitope profiling: A biomarker for functional cure.

Renae WalshRachel HammondLilly YuenJoshua DeerainTanya O'DonnellThomas LearyGavin ClohertyAnuj GaggarKathryn KitrinosMani SubramanianDarren Wong Stephen Locarnini

Published in: Liver international : official journal of the International Association for the Study of the Liver (2019)

The detection of HBsAg CPs by epitope mapping represents a novel viral biomarker, reflecting an emerging anti-HBs selection pressure prior to functional cure.

Keyphrases

hepatitis b virus
monoclonal antibody
high resolution
loop mediated isothermal amplification
quantum dots