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Tingible body macrophages: Gargantuan chameleons of the germinal center.

Elisa Madeleine BaudonMarc Bajenoff
Published in: The Journal of experimental medicine (2023)
Tingible body macrophages in lymph node are involved in cleaning up debris from apoptotic B cells. Gurwisz et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20222173) and Grootveld et al. (2023. Cell.https://doi.org/10.1016/j.cell.2023.02.004) report how tingible body macrophages, originating from tissue-resident macrophages, clear apoptotic B cells in the germinal center using a "stand-hunting" strategy.
Keyphrases
  • lymph node
  • cell death
  • single cell
  • cell therapy
  • squamous cell carcinoma
  • stem cells
  • early stage
  • bone marrow