Mice infected with Mycobacterium tuberculosis are resistant to secondary infection with SARS-CoV-2.

Oscar Rosas MejiaErin S GloagJianying LiMarisa Ruane-FosterTiffany A ClaeysDaniela FarkasLaszlo FarkasGang XinRichard T Robinson

Published in: bioRxiv : the preprint server for biology (2021)

Mycobacterium tuberculosis (Mtb) and SARS-CoV-2 (CoV2) are distinct organisms which both cause lung disease. We report the surprising observation that Mtb-infected mice are resistant to secondary infection with CoV2, with no impact on Mtb burden and resistance associating with lung T and B cell expansion.

Keyphrases

mycobacterium tuberculosis
sars cov
respiratory syndrome coronavirus
pulmonary tuberculosis
high fat diet induced
coronavirus disease
type diabetes
wild type
adipose tissue