Clinical relevance of inflammation on rectal biopsy for Hirschsprung disease: An outcomes analysis.
Dimitra M LotakisNathan S RubalcavaNatalie M LopyanAmer HeiderRaja RabahK Elizabeth SpeckMarcus D JarboePeter F EhrlichMatthew W RallsPublished in: Journal of pediatric gastroenterology and nutrition (2023)
Our study suggests inflammation on diagnostic rectal biopsy for HSCR is associated with increased anastomotic leak rates. While additional prospective studies are indicated, attention to methods of mitigating inflammation and confirming its resolution before definitive pull-through may be of benefit for improving clinical outcomes in patients found with inflammation on diagnostic rectal biopsy.
Keyphrases