Evolving phenotype of systemic lupus erythematosus in Caucasians: low incidence of lupus nephritis, high burden of neuropsychiatric disease and increased rates of late-onset lupus in the 'Attikon' cohort.
Dionysis S NikolopoulosM KostopoulouA PietaT KarageorgasD TseronisK ChavatzaS FloudaP RapsomanikiA BanosE KremasmenouV TzavaraP KatsimbriA FanouriakisD T BoumpasPublished in: Lupus (2020)
In this cohort of Caucasian patients, lupus nephritis is not as common as in older cohorts, while neuropsychiatric disease is emerging as a major frontier in lupus prevention and care. These data may help to document changes in the natural history and treatment of SLE over time and may have implications for its early recognition and management.
Keyphrases
- systemic lupus erythematosus
- late onset
- disease activity
- early onset
- end stage renal disease
- newly diagnosed
- risk factors
- ejection fraction
- healthcare
- rheumatoid arthritis
- chronic kidney disease
- palliative care
- physical activity
- prognostic factors
- patient reported outcomes
- community dwelling
- combination therapy
- patient reported
- deep learning
- artificial intelligence
- data analysis