Germline multigene panel testing in acute and chronic pancreatitis.

Mitchell L RamseyBrandie HealdYevgeniya GokunJosie BakerJ Royce GroceSamuel HanPhil A HartSomashekar G KrishnaLuis F LaraPeter J LeeGeorgios I PapachristouRachel PearlmanSarah PollMaegan E RobertsPeter P Stanich

Published in: PloS one (2024)

The highest prevalence of pathogenic variants is seen in younger individuals with a positive family history of pancreatitis. However, clinically meaningful results are identified in older subjects, suggesting that genetic counseling and testing should be considered for all age groups.

Keyphrases

copy number
liver failure
risk factors
physical activity
genome wide
drug induced
middle aged
aortic dissection
oxidative stress
intensive care unit
hiv testing
dna damage
men who have sex with men
hiv infected