Association of Nephronophthisis 4 genetic variation with cardiorenal syndrome and cardiovascular events in Japanese general population: the Yamagata (Takahata) study.

Yoichiro OtakiTetsu WatanabeJunya SatoYuta KobayashiTomonori AonoYuji SaitoJun GotoHiroki TakahashiTakanori ArimotoHidenori SatoTsuneo KontaYoshiyuki UenoMasafumi Watanabe

Published in: Heart and vessels (2021)

Genetic variations in the NPHP4 gene were associated with CRS and cardiovascular events in the general population, suggesting that it may facilitate the early identification of high-risk subjects with CRS and cardiovascular events.

Keyphrases

cardiovascular events
coronary artery disease
cardiovascular disease
genome wide
copy number
dna methylation
gene expression
transcription factor
genome wide identification