Primary splenic histiocytic sarcoma associated with hemophagocytic lymphohistiocytosis: A case report and review of literature of next-generation sequencing involving FLT3, NOTCH2, and KMT2A mutations.
Nelson MontalvoJorge Lara-EndaraLigia RedrobánMaría LeivaChristian ArmijosLeonardo RussoPublished in: Cancer reports (Hoboken, N.J.) (2021)
Primary splenic histiocytic sarcoma is one of the rarest tumors of the hematopoietic system. We report the first case with mutations in FLT3, NOTCH2, and KMT2A, and associated hemophagocytic lymphohistiocytosis.