A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice.

Marieke H SchoemakerRobert KleemannMartine C MorrisonJoanne VerheijKanita SalicEric A F van TolTeake KooistraPeter Y Wielinga

Published in: PloS one (2017)

A combination of eHC, ARA, DHA and LGG attenuates obesity and associated cardiometabolic diseases (NAFLD, atherosclerosis) in LDLr-/-.Leiden mice. The observed reduction of inflammation in adipose tissue and in the liver provides a rationale for these comprehensive health effects.

Keyphrases

high fat diet induced
insulin resistance
adipose tissue
metabolic syndrome
weight loss
cardiovascular disease
high fat diet
type diabetes
oxidative stress
weight gain
physical activity