NAFLD Is Associated With Quiescent Rather Than Active Crohn's Disease.
Scott A McHenryMatthew GloverAli AhmedQuazim AlayoMaria ZulfiqarDaniel R LudwigMatthew A CiorbaNicholas O DavidsonParakkal DeepakPublished in: Inflammatory bowel diseases (2023)
Quiescent CD is associated with risk of NAFLD. These findings suggest potentially distinct pathogenic mechanisms of NAFLD in patients with CD compared with the prevailing leaky gut hypothesis proposed for individuals without inflammatory bowel disease. Future validation and mechanistic studies are needed to dissect these distinct disease modifying factors.