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Optimal echocardiographic assessment of myocardial dysfunction for arrhythmic risk stratification in phospholamban mutation carriers.

Karim TahaTom E VerstraelenRemco de BrouwerRianne H A C M de Bruin-BonMaarten J CramerWouter P Te RijdtBerto J BoumaRudolf A de BoerPieter A DoevendansFolkert W AsselbergsArthur A M WildeMaarten P van den BergArco J Teske
Published in: European heart journal. Cardiovascular Imaging (2021)
LVMD has incremental prognostic value on top of LVEF in PLN p.Arg14del mutation carriers, particularly in those with preserved LVEF. The '45/45' rule is a practical approach to echocardiographic risk stratification in this challenging group of patients. This approach may also have added value in other diseases where LVEF deterioration is a relative late marker of myocardial dysfunction.
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