Comparison of 5 Different Rat Models to Establish a Standard Animal Model for Research Into Interstitial Cystitis.
Phil Hyun SongSo Young ChunJae Wook ChungYeon-Yong KimHyo-Jung LeeJun Nyung LeeYun Sok HaEun Sang YooTae Gyun KwonJeongshik KimDae Hwan KimBum Soo KimPublished in: International neurourology journal (2017)
Among the 5 different agents, the injection of UPK generated the most effective IC animal model, showing consequent urothelial barrier loss, inflammatory reaction, tissue fibrosis stimulation, and persistent hyperactive bladder.