The Antibody Response to SARS-CoV-2 Infection.
Linda HuestonJen KokAyla GuiboneDamien McDonaldGeorge HoneJames GoodwinIan CarterKerri BasileIndy SandaraduraSusan MaddocksVitali SintchenkoNicole GilroySharon ChenDominic E DwyerMatthew V N O'SullivanPublished in: Open forum infectious diseases (2020)
Measurement of SARS-CoV-2-specific antibody by IFA is an accurate method to diagnose COVID-19. Serological testing should be incorporated into diagnostic algorithms for SARS-CoV-2 infection to identify additional cases where NAT was not performed and resolve cases where false-negative and false-positive NATs are suspected. The majority of individuals develop robust antibody responses following infection, but the duration of these responses and implications for immunity remain to be established.