Objective sleep profile in LGI1/CASPR2 autoimmunity.

Michelle F DevineJohn C FeemsterElizabeth A LieskeStuart J McCarterDavid J SandnessTyler SteelePaul C TimmJay MandrekarBradley F BoeveMichael H SilberDivyanshu DubeyAndrew McKeonErik K St Louis

Published in: Sleep (2022)

LGI1/CASPR2-IgG autoimmunity is associated with prominent dream enactment, insomnia, RSWA, sleep apnea, and shallower sleep. Polysomnography provides objective disease markers in LGI1+/CASPR2+ autoimmunity and immunotherapy may benefit associated sleep disturbances.

Keyphrases

sleep apnea
sleep quality
obstructive sleep apnea
physical activity
positive airway pressure