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Glymphatic system dysfunction in temporal lobe epilepsy patients with hippocampal sclerosis.

Dong Ah LeeBong Soo ParkJunghae KoSi Hyung ParkYoo Jin LeeIl Hwan KimJin Han ParkKang Min Park
Published in: Epilepsia open (2022)
Our findings showed that the DTI-ALPS index was significantly lower in TLE patients with HS than in healthy controls, indicating the presence of glymphatic system dysfunction in TLE patients with HS. Our study also suggests that the DTI-ALPS method may be useful for evaluating glymphatic system function in epilepsy.
Keyphrases
  • temporal lobe epilepsy
  • oxidative stress
  • white matter
  • multiple sclerosis