Positive STAT5 Protein and Locus Amplification Status Predicts Recurrence after Radical Prostatectomy to Assist Clinical Precision Management of Prostate Cancer.

Bassem R HaddadAndrew EricksonVindhya UdhanePeter S LaVioletteJanice D RoneMarkku A KallajokiWilliam A SeeAntti Sakari RannikkoTuomas MirttiMarja T Nevalainen

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)

Our results highlight potential for a novel precision medicine concept based on a pivotal role of STAT5 status in improving selection of prostate cancer patients who are candidates for early adjuvant interventions to reduce the risk of recurrence.

Keyphrases

prostate cancer
radical prostatectomy
cell proliferation
early stage
physical activity
nucleic acid
amino acid
risk assessment
small molecule
label free