Plasma neurofilament light chain levels and cognitive testing as predictors of fast progression in Alzheimer's disease.

Roberto SantangeloFederica AgostaFrancesco MasiEdoardo Gioele SpinelliGiordano CecchettiFrancesca CasoAlessandra MandelliRosalinda CardamoneAlessandra BarbieriRoberto FurlanGiuseppe MagnaniMassimo Filippi

Published in: European journal of neurology (2021)

An easily applicable algorithm, including plasma NfL measurement and two neuropsychological tests worldwide adopted in clinical practice (SVF and CDT), may allow clinicians to reliably stratify AD patients in relation to the risk of fast cognitive decline.

Keyphrases

cognitive decline
mild cognitive impairment
clinical practice
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
machine learning
palliative care
deep learning
prognostic factors
cerebrospinal fluid
patient reported