Radon Exposure-induced Genetic Variations in Lung Cancers among Never Smokers.

Jung Ran Choi Sang-Baek Koh Hye Ryun Kim Hyojin Lee Dae Ryong Kang

Published in: Journal of Korean medical science (2018)

We identified that CHD4 rs74790047, TSC2 rs2121870, and AR rs66766408 are found to be common exonic mutations in both lung cancer patients and normal individuals exposed to radon indoors. Further analysis is needed to determine whether these genes are completely responsible for LCINS exposed to residential radon.

Keyphrases

genome wide
smoking cessation
diabetic rats
air pollution
gene expression
dna methylation
drug induced
bioinformatics analysis