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Pre-Transplantation Strategies for Infectious Disease Mitigation and Prevention.

Taylor Heald-SargentMarian G MichaelsMonica I Ardura
Published in: Journal of the Pediatric Infectious Diseases Society (2024)
Pediatric Infectious Disease (ID) clinicians play a critical role in helping prevent and mitigate infectious risks in children peri- and post-transplantation. Prevention starts during the pre-transplant evaluation and persists throughout the solid organ transplant and hematopoietic cell transplant continuum. The pre-transplant evaluation is an opportunity to screen for latent infections, plan preventative strategies, optimize immunizations, and discuss risk mitigation practices. An ideal pre-transplant evaluation establishes a relationship with the family that further promotes post-transplant infectious risk reduction. This manuscript builds on shared pediatric ID prevention strategies, introduces updated ID testing recommendations for transplant donors/candidates, highlights emerging data, and identifies ongoing knowledge gaps that are potential areas of research.
Keyphrases
  • infectious diseases
  • healthcare
  • climate change
  • primary care
  • cell therapy
  • bone marrow
  • single cell
  • palliative care
  • genome wide
  • human health
  • breast cancer risk