Oxidative Stress-Related Endothelial Damage in Vascular Depression and Vascular Cognitive Impairment: Beneficial Effects of Aerobic Physical Exercise.
Maria LucaAntonina LucaPublished in: Oxidative medicine and cellular longevity (2019)
Oxidative stress- (OS-) related endothelial damage is involved in the occurrence and progression of several disorders, such as vascular depression and dementia. It has been reported that moderate, aerobic, physical exercise could reduce OS and inflammation, thus limiting the cardiovascular risk factors while improving endothelial homeostasis, mood, and cognition. In this review, we will discuss about the role of OS and OS-related endothelial damage in vascular depression and vascular cognitive impairment. Then, we will comment on the effects of physical exercise on both disorders.
Keyphrases
- oxidative stress
- cognitive impairment
- cardiovascular risk factors
- endothelial cells
- depressive symptoms
- sleep quality
- dna damage
- mild cognitive impairment
- high intensity
- ischemia reperfusion injury
- diabetic rats
- induced apoptosis
- cardiovascular disease
- risk assessment
- bipolar disorder
- metabolic syndrome
- physical activity
- drug induced