Sarcoma Subgrouping by Detection of Fusion Transcripts Using NanoString nCounter Technology.
Javal ShethAnthony ArnoldoYunan ZhongPaula MarranoCarlos PereiraScott RyallPaul ThornerCynthia HawkinsGino R SomersPublished in: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society (2018)
Multiplexed interrogation for sarcoma-specific fusion transcripts using NanoString technology is a reliable approach for molecular diagnosis of pediatric sarcomas and works well with FFPE tissues. Future work will involve validating additional sarcoma fusion transcripts as well as determining the optimal workflow for diagnostic purposes.