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γ-Secretase inhibition affects viability, apoptosis, and the stem cell phenotype of endometriotic cells.

Laura Ramirez WilliamsKathrin BrüggemannMarina HubertNurjannah AchmadLudwig KieselSebastian D SchäferBurkhard GreveMartin Götte
Published in: Acta obstetricia et gynecologica Scandinavica (2019)
Our in vitro data suggest that application of GSI may be a worthwhile approach in the treatment of endometriosis that warrants further investigation.
Keyphrases
  • cell cycle arrest
  • stem cells
  • induced apoptosis
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • pi k akt
  • big data
  • signaling pathway
  • bone marrow