Obstructive Sleep Apnea and Subclinical Interstitial Lung Disease in the Multi-Ethnic Study of Atherosclerosis (MESA).
John S KimAnna J PodolanczukPriya BorkerSteven M KawutGanesh RaghuJoel D KaufmanKaren D Hinckley StukovskyEric A HoffmanR Graham BarrDaniel J GottliebSusan S RedlineDavid J LedererPublished in: Annals of the American Thoracic Society (2018)
Moderate to severe OSA is associated with subclinical ILD and with evidence of alveolar epithelial injury and extracellular matrix remodeling in community-dwelling adults, an association that is strongest among normal-weight individuals. These findings support the hypothesis that OSA might contribute to early ILD.