The Antiallodynic Effect of Nefopam on Vincristine-Induced Neuropathy in Mice.

Jin Young Lee Woo-Seog SimNoo Ree ChoBae Wook KimJeong Yeon MoonHue Jung Park

Published in: Journal of pain research (2020)

Intraperitoneally administered nefopam yielded a dose-dependent attenuation of mechanical allodynia and decreased neurokinin-1 receptor concentration, suggesting that the neurokinin-1 receptor is involved in the antiallodynic effects of nefopam in vincristine neuropathy.

Keyphrases

high glucose
neuropathic pain
diabetic rats
high fat diet induced
drug induced
stress induced