Role of tissue factor in delayed bone repair induced by diabetic state in mice.

Hiroki EharaKohei TatsumiYoshimasa TakafujiNaoyuki KawaoMasayoshi IshidaKiyotaka OkadaNigel MackmanHiroshi Kaji

Published in: PloS one (2021)

Low TF state was associated with enhanced bone repair delay induced by diabetic state in mice. The TF-induced suppression of bone remodeling may be a contributing factor to the protective effects of TF against delayed bone repair in a diabetic state.

Keyphrases

bone mineral density
type diabetes
soft tissue
bone loss
bone regeneration
wound healing
postmenopausal women
high fat diet induced
body composition
oxidative stress
adipose tissue
drug induced
endothelial cells