Choclo virus (CHOV) recovered from deep metatranscriptomics of archived frozen tissues in natural history biorepositories.

Paris S HammWilliam L JohnsonRobert A NofchisseyJacqueline R SalazarPublio GonzalezSamuel M GoodfellowJonathan L DunnumSteven B BradfuteBlas ArmiénJoseph A CookDaryl B DommanDarrell L Dinwiddie

Published in: PLoS neglected tropical diseases (2024)

Viruses occurring at extremely low abundances can be recovered from deep metatranscriptomics of archival tissues housed in research natural history museum biorepositories. Our efforts resulted in the second CHOV genome publicly available. This genomic data is important for future surveillance and diagnostic tools as well as understanding the evolution and pathogenicity of CHOV.

Keyphrases

gene expression
public health
electronic health record
current status
copy number
quality improvement
genome wide
biofilm formation
dna methylation
machine learning
cystic fibrosis
pseudomonas aeruginosa
genetic diversity