Clinical and cost outcomes following genomics-informed treatment for advanced cancers.
Deirdre WeymannSamantha PollardBrandon ChanEmma TitmussAlexandra BohmJanessa LaskinSteven J M JonesErin PleasanceJessica NelsonAlexandra FokHoward LimAly KarsanDaniel J RenoufKasmintan A SchraderSophie SunStephen YipDavid F SchaefferMarco A MarraDean A RegierPublished in: Cancer medicine (2021)
Genomics-informed treatment had a statistically significant effect on TTD compared to standard care treatment, but at increased treatment costs. Within-cohort evidence generated through this single-arm study informs the early-stage comparative effectiveness of precision oncology.