The prognostic value of serum levels of a proliferation-inducing ligand (APRIL) in treatment-naïve patients with chronic lymphocytic leukemia
Sinem Nihal EsatogluDilek KeskinAhmet Emre EskazanTuğrul ElverdiAyse SalihogluMuhlis Cem ArŞeniz ÖngörenZafer BaşlarYildiz AydinHafize UzunTeoman SoysalPublished in: Turkish journal of medical sciences (2021)
sAPRIL, a simple, promising blood test which can be measured by ELISA, will likely obtain a place in the wide range of prognostic markers in CLL. Prospective large-scale studies are required to validate and confirm the feasibility of the proposed cut-off level of 2.04 ng/mL as a predictor of time to treatment in treatment-naïve CLL patients.