The prognostic value of serum levels of a proliferation-inducing ligand (APRIL) in treatment-naïve patients with chronic lymphocytic leukemia

Sinem Nihal Esatoglu Dilek Keskin Ahmet Emre Eskazan Tuğrul Elverdi Ayse Salihoglu Muhlis Cem Ar Şeniz Öngören Zafer Başlar Yildiz Aydin Hafize Uzun Teoman Soysal

Published in: Turkish journal of medical sciences (2021)

sAPRIL, a simple, promising blood test which can be measured by ELISA, will likely obtain a place in the wide range of prognostic markers in CLL. Prospective large-scale studies are required to validate and confirm the feasibility of the proposed cut-off level of 2.04 ng/mL as a predictor of time to treatment in treatment-naïve CLL patients.

Keyphrases

chronic lymphocytic leukemia
end stage renal disease
signaling pathway
ejection fraction
peritoneal dialysis