Circulating microRNA-21 is an early predictor of ROS-mediated damage in subjects with high risk of developing diabetes and in drug-naïve T2D.

Lucia La SalaSimona Mrakic-SpostaElena TagliabueFrancesco PrattichizzoStefano MicheloniElena SangalliClaudia SpecchiaAnna Chiara UccellatoreSilvia LupiniGaia SpinettiPaola de CandiaAntonio Ceriello

Published in: Cardiovascular diabetology (2019)

our data demonstrate that microRNA-21 is associated with prediabetic status and exhibits predictive value for early detection of glucose imbalances. These data could provide novel clues for miR-based biomarkers to evaluate diabetes.

Keyphrases

type diabetes
cardiovascular disease
electronic health record
glycemic control
big data
cell proliferation
long non coding rna
dna damage
cell death
blood glucose
long noncoding rna
data analysis
machine learning
reactive oxygen species
deep learning
weight loss