The Utility of 18F-NaF-PET/CT in Measuring the Metabolic Activity of Aging Spine: Implications for Osteoporosis.

Peter Sang Uk ParkDavid A RestoNavpreet KhuranaWilliam Y RaynorThomas J WernerPoul Flemming Høilund-CarlsenAbass Alavi

Published in: Spine (2023)

NaF-PET/CT detects decreased vertebral bone turnover with aging particularly in females. Measured NaF uptake increased with PET acquisition time after tracer injection, which must be considered in follow-up studies monitoring disease development and treatment effects.

Keyphrases

pet ct
bone mineral density
positron emission tomography
postmenopausal women
body composition
combination therapy
computed tomography
pet imaging
case control
replacement therapy