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Integrative analysis of transcriptome-wide association study and mRNA expression profile identified risk genes for bipolar disorder.

Runxu YangRui WangDongyan ZhaoKun LianBinli ShangLei DongXuejuan YangXinglun DangDuo SunYuqi Cheng
Published in: Neuroscience letters (2024)
We found a set of BD-associated genes and pathways, validating the important role of neurodevelopmental abnormalities, inflammatory responses, and mitochondrial dysfunction in the pathology of BD, offering novel information for comprehending the genetic basis of BD.
Keyphrases
  • single cell
  • rna seq
  • bipolar disorder
  • genome wide
  • major depressive disorder
  • genome wide identification
  • dna methylation
  • bioinformatics analysis
  • copy number
  • healthcare
  • gene expression