Acquired Factor XIII Deficiency Is Common during ECMO Therapy and Associated with Major Bleeding Events and Transfusion Requirements.

Matthias NoitzRoxane BrooksJohannes SzaszDennis JennerCarl BöckNiklas KrennerMartin W DünserJens Meier

Published in: Journal of clinical medicine (2023)

In this retrospective single centre study, acquired factor XIII deficiency was observed in 69% of adult ECMO patients with a high bleeding risk. Factor XIII deficiency was associated with higher rates of major bleeding events and transfusion requirements.

Keyphrases

extracorporeal membrane oxygenation
atrial fibrillation
acute respiratory distress syndrome
cardiac surgery
replacement therapy
risk factors
respiratory failure
young adults