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Plasma albumin levels predict risk for nonsurvivors in critically ill patients with COVID-19.

Ju-Yi LiMeng LiShasha ZhengMenglan LiMinghua ZhangMinxian SunXiang LiAi-Ping DengYi CaiHongmei Zhang
Published in: Biomarkers in medicine (2020)
Aim: We aimed to explore the biomarkers for disease progression or the risk of nonsurvivors. Materials & methods: This study included 134 hospitalized patients with confirmed COVID-19 infection. The outcome of moderate versus severe versus critically ill patients and survivors versus nonsurvivors were compared. Results: An increase in the severity of COVID-19 pneumonia was positively associated with lower levels of platelets and albumin (all p < 0.05). In the critical group, the plasma levels of albumin continued to have a significant association for the risk of nonsurvivors (p < 0.05), even after adjusting for confounding factors. Conclusion: Albumin levels could be used as an independent predictor of the risk of nonsurvivors in critically ill patients with COVID-19.
Keyphrases
  • coronavirus disease
  • young adults
  • intensive care unit
  • high intensity
  • early onset
  • acute respiratory distress syndrome
  • community acquired pneumonia