Comparative Profiling of Milk Somatic Cells Proteomes Revealed Key Players in Mammary Immune Mechanisms During Mastitis in Tropical Sahiwal (Bos indicus) Cows.

Lija SatheesanPriyanka M KitturMohanned Naif AlhussienSeema KaranwalMadhusoodan A PRani AlexAarti KambojAjay Kumar Dang

Published in: Proteomics. Clinical applications (2024)

These findings provide essential information on proteomic profiling in milk SCs and contribute valuable insights into immune-related proteins regulated during mastitis in dairy cows. Further, validated proteins (Vanin 2, MINK1, and Thrombospondin 1) offer potential inflammatory biomarkers for early mastitis detection in dairy cows.

Keyphrases

dairy cows
single cell
induced apoptosis
label free
cell cycle arrest
oxidative stress
transcription factor
endoplasmic reticulum stress
healthcare
loop mediated isothermal amplification
signaling pathway
real time pcr
cell death
gene expression
cell proliferation
human health
dna methylation
sensitive detection