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Hints for control of infection in unique extrahepatic vertebral alveolar echinococcosis.

Jean François FaucherCécile Descotes-GenonBruno HoenJoël GodardSophie FélixSébastien AubryOleg BlagosklonovFrédéric GrenouilletMarie-Pascale BrientiniCarine RichouSolange Bresson-HadniCatherine Chirouze
Published in: Infection (2016)
The prognosis of vertebral alveolar echinococcosis (AE) is poor. We report on the unique outcome of a patient with preexisting liver cirrhosis, in whom a diagnosis of vertebral AE was established on vertebral histopathology (D4 corporectomy in 2010 for paraplegia). Therapeutic drug monitoring of albendazole (ABZ) showed that a low dosage was appropriate. The patient recovered and ABZ withdrawal was decided in 2014, with no relapse 18 months later. In this patient, infection was purely or mainly localized in the dorsal spine, and this may have been favored by liver cirrhosis. A longer follow-up is, however, needed to confirm cure.
Keyphrases
  • bone mineral density
  • case report
  • spinal cord
  • body composition