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Zosteriform multidermatomal nodules and plaques in a case of lepromatous leprosy: an uncommon presentation.

Sinu Rose MathachanKabir SardanaArvind AhujaMallika LavaniaDiksha Agrawal
Published in: Tropical doctor (2020)
Leprosy is caused by the obligate intracellular organism Mycobacterium leprae which mainly affects the skin and nervous system. The course of the disease is determined by host immunity, it is thus believed that in lepromatous leprosy (LL), all manifestations are bilaterally symmetrical. This is because of the inability of the host to mount an adequate cell-mediated immune response, resulting in widespread haematogenous dissemination of bacilli. Varied manifestations of LL have been reported; however, a multidermatomal pattern of nodules is hitherto unreported and we suggest a hypothesis for its presentation.
Keyphrases
  • immune response
  • mycobacterium tuberculosis
  • single cell
  • case report
  • gram negative
  • cell therapy
  • soft tissue
  • dendritic cells
  • toll like receptor
  • mesenchymal stem cells