Gongronema latifolium leaf extract modulates hyperglycaemia, inhibits redox imbalance and inflammation in alloxan-induced diabetic nephropathy.
Oluwafemi Adeleke OjoOlukemi Adetutu OsukoyaLisa Ilobekemen EkakitieBasiru Olaitan AjiboyeBabatunji Emmanuel OyinloyePrecious Eseose AgboinghaleAbidemi Paul KappoPublished in: Journal of diabetes and metabolic disorders (2020)
The data from this study suggest that G. latifolium modulates glucose homeostasis as well as inhibiting redox imbalance and inflammation in diabetic rats, which may be attributed to the effects of its phytochemical constituents such as saponins, flavonoids and alkaloids. It also indicated that inhibition of inflammatory cytokines and redox imbalance are likely mechanisms by which G. latifolium leaf exert its antidiabetic action.