HALFMOON TomoTherapy (Helical ALtered Fractionation for iMplant partial OmissiON): implant-sparing post-mastectomy radiotherapy reshaping the clinical target volume in the reconstructed breast.
Maria Cristina LeonardiRuggero SpotoEleonora MigliettaSara TrivellatoEliana La RoccaRosa LuraschiPaola GrossoFrancesca De LorenziCristiana FodorSamantha DicuonzoVeronica Dell'AcquaMarianna Alessandra GerardiAnna MorraClaudia Maria FranciaMario RietjensViviana Enrica GalimbertiPaolo VeronesiRoberto OrecchiaFederica CattaniBarbara Alicja Jereczek-FossaPublished in: Journal of cancer research and clinical oncology (2019)
The HALFMOON approach is technically feasible and resulted in high-dose conformity of the target with a significant reduction of radiation dose delivered to implant and other organs. A clinical study is needed to assess the impact on reconstruction cosmetic outcome and local control.