Immunogenicity and Reactogenicity of High-dose or Standard-dose Influenza Vaccine in a Second Consecutive Influenza Season.
Hannah BahakelAndrew J SpiekerHaya HayekJennifer E SchusterLubna HamdanDaniel E DulekCarrie L KitkoTess StopczynskiEinas BatarsehZaid HaddadinLaura S StewartAnna StahlMolly PotterHerdi RahmanJustin AmarinSpyros A KalamsClaire E BocchiniElizabeth A MoultonSusan E CoffinMonica I ArduraRachel L WattierGayatri Shankar ChilambiMichael GrimleyGrant PaulsenChristopher J HarrisonJason FreedmanPaul A CarpenterJanet A EnglundFlor M MunozLara A Danziger-IsakovNatasha Halasanull nullPublished in: The Journal of infectious diseases (2024)
A single dose of HD-TIV or SD-QIV was more immunogenic in year two than two doses of the same formulation in year one. Reactogenicity was comparable between groups. One dose of influenza vaccine may be sufficient after a two-dose schedule in the prior year post-HCT.